- Save $15 on your prescription
- Prescription discounts at access2wellness.com
- American Family Physician aafp.org
- Centers for Disease Control cdc.gov
WHAT ARE COMMON TYPES OF BACTERIAL RESPIRATORY TRACT INFECTIONS?
There are many different kinds of bacterial respiratory tract infections (RTIs), including sinusitis, bronchitis, and pneumonia. Common symptoms of RTIs include nasal congestion, runny nose, scratchy throat, cough, and fever.
Sometimes infections are caused by viruses rather than by bacteria. Examples include viral infections in the sinuses and lungs, such as the common cold or flu. Antibiotics, including LEVAQUIN®, do not kill viruses.
Bronchitis is a condition that affects the bronchial tubes—the 2 branches of the windpipe that lead to the lungs. Bronchitis can either be acute (short term following a cold in an otherwise healthy person) or chronic (generally occurs in a person with COPD [chronic obstructive pulmonary disease]). When you have chronic bronchitis, there is long-lasting inflammation of the bronchial tubes that causes shortness of breath, and coughing with discolored mucus that lasts for months or even years.
If you have COPD or chronic bronchitis, your bronchial tubes are more likely to become infected by bacteria because they are already irritated. This can cause symptoms to feel worse than usual. Such an infection is called an acute bacterial exacerbation of chronic bronchitis, or ABECB.
ABECB can last up to 10 days. During that time, your symptoms will be worse than usual. After your ABECB infection has cleared, you will still have chronic bronchitis.
Who is at risk?
Smokers are at higher risk. One of the most important steps in the treatment of chronic bronchitis is to stop smoking. People exposed to other lung irritants over a long period of time are also at risk.
What are the signs and symptoms?
- Increased production of mucus (sputum/phlegm)
- Increased difficulty breathing
- Chest pain or discomfort
How does it develop?
- Cigarette smoking is the primary cause of chronic bronchitis. Inhaled tobacco smoke irritates the airways, which respond by producing mucus. Smoke causes lung inflammation, which can lead to further tissue damage
- Inhaling chemical fumes, dust, and other substances can potentially lead to chronic bronchitis
Does LEVAQUIN® treat bronchitis?
LEVAQUIN® is one of the treatment options your healthcare professional may consider when you have an acute bacterial exacerbation of chronic bronchitis. It is used in adults 18 years or older to treat ABECB due to certain germs called methicillin-susceptible Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis.
Remember, only your healthcare professional can determine what type of infection you have, and what the appropriate treatment options are. If you are diagnosed with an acute bacterial sinus infection, you may be prescribed LEVAQUIN® or another antibiotic. If your healthcare professional feels your infection is caused by a virus, antibiotics will not help.
Be sure to follow the instructions given by your healthcare professional and pharmacist. Don't stop taking your prescription as soon as you feel better—it's important to complete your medicine as prescribed to kill the bacteria and halt your infection. Finishing your prescription will also help to lower the chance that bacteria will become resistant. You should stop taking LEVAQUIN® if you experience tendon effects, have a serious allergic reaction, or your healthcare professional tells you to stop.
See Important Safety Information
IMPORTANT SAFETY INFORMATION
Fluoroquinolones, including LEVAQUIN®, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Call your healthcare professional right away at the first sign of tendon pain, swelling, or inflammation. You should stop taking LEVAQUIN® until tendinitis or tendon rupture have been ruled out, and avoid exercise and using the affected area.
LEVAQUIN® is contraindicated in persons with known hypersensitivity to LEVAQUIN® or other fluoroquinolone antibiotics. Serious and occasionally fatal allergic reactions, as well as some of unknown origin, have been reported in patients receiving therapy with fluoroquinolones, including LEVAQUIN®. These reactions may occur following the first dose or multiple doses. The drug should be discontinued at the first appearance of a skin rash, hives, or other symptoms of an allergic reaction. Skin rash may be a sign of a more serious reaction to LEVAQUIN®.
Hepatotoxicity (liver damage) has been reported in patients receiving LEVAQUIN®. Call your healthcare professional right away if you have unexplained symptoms such as: nausea or vomiting, stomach pain, fever, weakness, abdominal pain or tenderness, itching, unusual or unexplained tiredness, loss of appetite, light colored bowel movements, dark colored urine or yellowing of your skin or the whites of your eyes.
Convulsions have been reported in patients receiving fluoroquinolone antibiotics including LEVAQUIN®. Tell your physician if you have a history of convulsions. Central nervous system disorders including convulsions, confusion, insomnia, depression, and anxiety may occur after the first dose. You should talk to your physician right away if you experience these or other changes in mood or behavior.
Changes in sensation and possible nerve damage (peripheral neuropathy) including pain, burning, tingling, numbness, and/or weakness have been reported.
Diarrhea that usually ends after treatment is a common problem caused by antibiotics. An intestinal infection (pseudomembranous colitis) can happen with most antibiotics, including LEVAQUIN®. Call your physician right away if you get watery diarrhea, diarrhea that does not go away, or bloody stools (with or without stomach cramps and fever). This can occur during or up to 2 months after the use of antibiotics.
In a few people, LEVAQUIN®, like some other antibiotics, has been linked to abnormal heart rhythms that can be dangerous. Tell your healthcare professional if you have a history of or currently have low potassium levels, abnormal heart rhythms, or are taking any medications for abnormal heart rhythms.
LEVAQUIN® can make your skin sensitive to the sun (photosensitivity) and the light from sunlamps and tanning beds. You could get severe sunburn, blisters, or swelling of your skin. Excessive exposure to the sun or UV light should be avoided.
Blood glucose disturbances have been reported with use of fluoroquinolones, usually in diabetic patients taking an oral anti-diabetes medicine or insulin.
If you develop any of these symptoms or side effects discussed above, contact your healthcare professional as soon as possible.
Antacids containing magnesium or aluminum, as well as sucralfate, metal cations such as iron, and multivitamin preparations with zinc, or Videx®* (didanosine) chewable/buffered tablets or the pediatric powder for oral solution, should not be taken within 2 hours before or after LEVAQUIN® administration. If you are taking warfarin, concurrent treatment with LEVAQUIN® has been associated with episodes of bleeding. Your physician should monitor you for evidence of bleeding and also monitor your anticoagulation tests closely.
LEVAQUIN® should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Because of the potential for serious adverse reactions from LEVAQUIN® in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
The risk-benefit assessment indicates that LEVAQUIN® is only appropriate in pediatric patients >6 months of age for treatment of inhalational anthrax (post-exposure). An increased chance of problems with the joints and tissues around the joints has been observed in pediatric patients receiving LEVAQUIN® and the safety in pediatric patients treated for more than 14 days has not been studied.
The most common adverse drug reactions (>3%) in US clinical trials were nausea, headache, diarrhea, insomnia, constipation, and dizziness.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
This product is available by prescription only. For information on Warnings, Precautions, Adverse Reactions, Drug Interactions, and Use in Specific Populations, please see Medication Guide and full Product Information, including Boxed Warning.
* Videx is a registered trademark of Bristol-Myers Squibb Company.
